Melanotan II
Also known as: MT-2, MT2, Melanotan 2
How It Works
Non-selective melanocortin receptor agonist that stimulates melanogenesis (skin tanning) and activates MC4R in the brain to increase sexual arousal and libido. Also reduces appetite.
What It's Used For
Administration
Safety & Side Effects
Possible Side Effects
- ⚠Nausea (common initially)
- ⚠Facial flushing
- ⚠Darkening of moles
- ⚠Spontaneous erections
- ⚠Appetite suppression
- ⚠Fatigue
Contraindications
- ✘Melanoma or history of melanoma
- ✘Multiple/atypical moles
- ✘Pregnancy
- ✘Cardiovascular disease
- ✘Autoimmune conditions
Research Summary
Developed at University of Arizona. Effective for tanning without UV exposure and sexual dysfunction. Safety concerns include potential melanoma risk from mole stimulation. PT-141 was derived from MT-II as a more targeted sexual health peptide.
References
- Dorr RT et al. Life Sci. 1996
- Hadley ME et al. Ann N Y Acad Sci. 2003
Legal & Availability
Research chemical / Not FDA-approved / Banned in some countries
This peptide requires a prescription from a licensed provider.
Dosing Protocol
Standard: 250-500mcg per dose
Frequency: Daily during loading, then 1-2x/week maintenance
Timing: Before sun exposure for tanning; evening for libido
Notes: Start at 250mcg to assess tolerance; nausea common at first
Stacks Well With
Full stacking protocols and cycling schedules available with Pro subscription.
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This information is for educational purposes only and is not medical advice. Do not use any peptide without consulting a qualified healthcare provider. BioRoot AI is a clinical decision support tool — not a medical provider.