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Dihexa

Also known as: N-hexanoic-Tyr-Ile-(6) aminohexanoic amide

ExperimentalCognitive EnhancementProvider Rx Required

How It Works

Angiotensin IV analog. Activates hepatocyte growth factor (HGF) system. Promotes synaptogenesis and neuronal connectivity. ~10 million times more potent than BDNF at forming new synapses.

What It's Used For

Cognitive enhancementNeuroplasticityMemoryNeurodegenerative support

Administration

Route: Oral, Subcutaneous injection

Typical Cycle: 2-4 weeks on, 2-4 weeks off

Safety & Side Effects

Possible Side Effects

⚠Limited data
⚠Headache
⚠Potential overstimulation

Contraindications

✘Active cancer (promotes HGF)
✘Pregnancy
✘Liver disease

Research Summary

Extraordinarily potent procognitive agent in animal studies. Promotes synaptogenesis via HGF/c-Met system. Very limited human data - use with caution.

References

McCoy AT et al. J Pharmacol Exp Ther. 2013

Legal & Availability

Research chemical

This peptide requires a prescription from a licensed provider.

Dosing Protocol

Standard: 10-20mg per dose

Frequency: Once daily

Timing: Morning

Notes: Very potent. Start low. Oral or SubQ. Limited human safety data.

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Unlock Full Dosing Protocol

Specific dosing, frequency, timing, cycling schedules, and stacking guidance are available with a BioRoot AI Pro subscription.

Stacks Well With

Semax

Cognitive enhancement, Neuroprotection

Selank

Anxiety reduction, Cognitive enhancement

Full stacking protocols and cycling schedules available with Pro subscription.

Is Dihexa Right for You?

Our AI analyzes your symptoms, labs, and medical history to determine if this peptide fits your protocol — and at what dose.

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This information is for educational purposes only and is not medical advice. Do not use any peptide without consulting a qualified healthcare provider. BioRoot AI is a clinical decision support tool — not a medical provider.