Semax
How It Works
Synthetic analog of ACTH(4-10). Neuroprotective peptide that increases BDNF, NGF, and modulates dopamine/serotonin. Enhances attention and memory formation.
What It's Used For
Administration
Safety & Side Effects
Possible Side Effects
- ⚠Irritability
- ⚠Hair loss (rare, typically with N-Acetyl Semax Amidate)
- ⚠Insomnia if taken late
Contraindications
- ✘Pregnancy
- ✘Seizure disorders (caution)
- ✘Hypertension
Research Summary
Approved in Russia and Ukraine for cognitive enhancement and stroke recovery. Increases BDNF and NGF. Demonstrated neuroprotective effects in ischemic brain injury.
References
- Levitskaya NG et al. Neurosci Behav Physiol. 2008
Legal & Availability
Approved in Russia / Research chemical elsewhere
Dosing Protocol
Standard: 200-600mcg per dose
Frequency: 1-3x daily
Timing: Morning and early afternoon (may affect sleep if taken late)
Notes: Nasal spray. Can be stimulating.
Stacks Well With
Full stacking protocols and cycling schedules available with Pro subscription.
Is Semax Right for You?
Our AI analyzes your symptoms, labs, and medical history to determine if this peptide fits your protocol — and at what dose.
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This information is for educational purposes only and is not medical advice. Do not use any peptide without consulting a qualified healthcare provider. BioRoot AI is a clinical decision support tool — not a medical provider.