Sermorelin
Also known as: Sermorelin Acetate, GRF 1-29
How It Works
Bioidentical GHRH analog consisting of the first 29 amino acids of endogenous GHRH. Stimulates natural pulsatile GH release from the pituitary without suppressing endogenous production.
What It's Used For
Administration
Safety & Side Effects
Possible Side Effects
- ⚠Injection site reactions
- ⚠Flushing
- ⚠Headache
- ⚠Dizziness
Contraindications
- ✘Active cancer
- ✘Pregnancy
- ✘Pituitary tumors
Research Summary
One of the earliest GHRH analogs with extensive clinical data. Previously FDA-approved (Geref) for GH deficiency diagnosis. Shows consistent GH elevation with excellent safety profile.
References
- Walker RF. Clin Interv Aging. 2006
- Merriam GR et al. J Clin Endocrinol Metab. 2001
Legal & Availability
Prescription required / Compounding pharmacy
Dosing Protocol
Standard: 200-300mcg per dose
Frequency: Once daily
Timing: Before bed
Notes: FDA-approved for pediatric GH deficiency testing; used off-label in adults
Stacks Well With
Ipamorelin
Anti-aging, Fat loss
GHRP-6
Growth hormone release, Appetite stimulation
BPC-157
Injury repair, Gut healing
Full stacking protocols and cycling schedules available with Pro subscription.
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This information is for educational purposes only and is not medical advice. Do not use any peptide without consulting a qualified healthcare provider. BioRoot AI is a clinical decision support tool — not a medical provider.