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KPV

Also known as: Lysine-Proline-Valine

Emerging ResearchImmune & Longevity

How It Works

C-terminal tripeptide of alpha-MSH. Potent anti-inflammatory effects via NF-kB pathway inhibition. Modulates gut inflammation.

What It's Used For

Gut inflammationIBD supportAutoimmune modulationSkin inflammationGeneral anti-inflammatory

Administration

Route: Oral, Subcutaneous injection, Topical

Typical Cycle: 4-8 weeks

Safety & Side Effects

Possible Side Effects

⚠Generally well tolerated
⚠Mild GI effects (oral)

Contraindications

✘Pregnancy

Research Summary

Tripeptide from alpha-MSH with potent anti-inflammatory effects. Inhibits NF-kB-mediated inflammation. Promising for inflammatory bowel conditions.

References

Brzoska T et al. Endocr Rev. 2008

Legal & Availability

Research chemical

Dosing Protocol

Standard: 200-500mcg per dose

Frequency: 1-2x daily

Timing: Any time

Notes: Can be used orally for gut inflammation or SubQ for systemic effects

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Unlock Full Dosing Protocol

Specific dosing, frequency, timing, cycling schedules, and stacking guidance are available with a BioRoot AI Pro subscription.

Stacks Well With

BPC-157

Injury repair, Gut healing

Thymosin Alpha-1

Immune enhancement, Chronic infections

Full stacking protocols and cycling schedules available with Pro subscription.

Is KPV Right for You?

Our AI analyzes your symptoms, labs, and medical history to determine if this peptide fits your protocol — and at what dose.

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This information is for educational purposes only and is not medical advice. Do not use any peptide without consulting a qualified healthcare provider. BioRoot AI is a clinical decision support tool — not a medical provider.