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Biotinoyl Tripeptide-1

Also known as: Biotinyl-GHK, Procapil component

Emerging ResearchHair & Skin

How It Works

Biotin-conjugated peptide that strengthens hair follicle anchoring in the dermal papilla. Reduces follicle aging by improving metabolic activity and blood flow to hair follicles.

What It's Used For

Hair loss preventionHair strengtheningFollicle anchoringThinning hairAlopecia support

Administration

Route: Topical

Typical Cycle: 3-6 months minimum for visible results

Safety & Side Effects

Possible Side Effects

⚠Mild scalp irritation
⚠Rarely: contact dermatitis

Contraindications

✘Biotin allergy

Research Summary

Component of Procapil, a studied hair growth complex. In vitro studies show improved follicle anchoring and reduced hair loss. Clinical evidence suggests prevention of hair thinning.

References

Jacquet A et al. Clin Cosmet Investig Dermatol. 2019

Legal & Availability

Available OTC as cosmetic ingredient

Dosing Protocol

Standard: 1-3% in topical formulation

Frequency: Daily

Timing: Evening application to scalp

Notes: Often combined with other hair peptides and minoxidil

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Unlock Full Dosing Protocol

Specific dosing, frequency, timing, cycling schedules, and stacking guidance are available with a BioRoot AI Pro subscription.

Stacks Well With

Copper Peptide AHK-Cu

Hair growth, Hair loss prevention

GHK-Cu

Skin rejuvenation, Wound healing

Full stacking protocols and cycling schedules available with Pro subscription.

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This information is for educational purposes only and is not medical advice. Do not use any peptide without consulting a qualified healthcare provider. BioRoot AI is a clinical decision support tool — not a medical provider.